主要研究细胞骨架及相关信号通路在皮肤、眼睛等器官发育与稳态中的功能，并探讨细胞骨架及相关信号通路的调控异常与肿瘤等疾病发生发展的关系。

1.        Wang D, Li Q, Yu Z, Zhao J, Hu M, Geng X, Liu X, Zhao S, Song T, Liu M, Li D, Zhao H, Zhou J. FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis. J Cell Biol. 2025 Oct 6;224(10):e202412224.

2.        Zhai D, Li L, Wang D, Wang W, Zhao S, Wang X, Chen C, Zhu Z, Bu W, Yang M, Yin H, Shan Y, Zhao H, Westlake CJ, Lu Q, Zhou J. TBC1D20 coordinates vesicle transport and actin remodeling to regulate ciliogenesis. J Cell Biol. 2025 Apr 4;224(4):e202406139.

3.        Hong R, Tan Y, Tian X, Huang Z, Wang J, Ni H, Yang J, Bu W, Yang S, Li T, Yu F, Zhong W, Sun T, Wang X, Li D, Liu M, Yang Y, Zhou J. XIAP-mediated degradation of IFT88 disrupts HSC cilia to stimulate HSC activation and liver fibrosis. EMBO Rep. 2024 Mar;25(3):1055-1074.

4.        Li T, Liu M, Yu F, Yang S, Bu W, Liu K, Yang J, Ni H, Yang M, Yin H, Hong R, Li D, Zhao H, Zhou J. Pathologically relevant aldoses and environmental aldehydes cause cilium disassembly via formyl group-mediated mechanisms. J Mol Cell Biol. 2024 Jul 1;16(1):mjad079.

5.        Yu F, Yang S, Ni H, Heng D, Wu X, Yang M, Zhang X, Cao Y, Pei Y, An D, Li D, Liu D, Liu L, Pan L, Chen Q, Zhu X, Zhou J. O-GlcNAcylation Regulates centrosome behavior and cell polarity to reduce pulmonary fibrosis and maintain the epithelial phenotype. Adv Sci. 2023 Dec;10(36):e2303545.

担任中国细胞生物学学会资深理事，天津市细胞生物学学会理事长。

主讲《细胞生物学》本科生课程、《细胞生物学进展》博士生课程等。